Focus on Alternative and Complementary Therapies
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Focus Alternat Complement Ther©2005 Pharmaceutical Press
Focus Altern Complement Ther 1998; 3: 194
Feverfew is a popular herbal remedy advocated for the prevention of migraine.
The aim of this systematic review was to review the evidence for or against the clinical effectiveness of feverfew for migraine prevention.
Literature searches were performed using the following databases: Medline, Embase, Biosis, CISCOM and the Cochrane Library (all from their inception to April 1998).
Only randomised, placebo-controlled, double-blind trials were included.
All articles were read by two independent reviewers. Data were extracted in a pre-defined, standardised fashion. The methodological quality of all trials was evaluated by the Jadad score.
Five trials met the inclusion/exclusion criteria. The majority favour feverfew over placebo. Yet important caveats exist.
The clinical effectiveness of feverfew in the prevention of migraine has not been established beyond reasonable doubt.
