Chinese researchers explored the clinical effect of three different dosage-forms of Zhishi Xiaopi Pill (ZSXPP) recipe on functional dyspepsia (FD). A total of 158 patients suffering from functional dyspepsia were included in this study and were randomly divided into four groups. Three groups of patients with FD were treated with three different dosage forms of ZSXPP, while the control group was treated with cisapride. The treatment outcome indicated that there was no difference in the total therapeutic efficacies of theses four groups. Plasma levels of motilin in FD patients were significantly increased by the treatment with ZSXPP. Impaired contraction function of the lower oesophageal sphincter in some FD patients was also improved.