A study sought to describe the pattern of CAM use among a group of patients with advanced breast cancer, to examine the main reasons for their CAM use, to identify patients’ information sources and their communication pattern with their physicians. Face-to-face structured interviews were conducted with advanced-stage breast cancer patients at a comprehensive oncology centre. Of the patients interviewed, 73% used CAM: relaxation/meditative techniques and herbal medicine were the most common. The most frequently cited primary reason for CAM use was to boost the immune system, the second, to treat cancer; however, these reasons varied depending on specific CAM therapy. Friends or family members and mass media were common primary information sources about CAM.