The aim of this RCT was to validate a single acupoint for relieving uraemic pruritus. Chinese researchers randomised 40 patients with refractory uraemic pruritus into two groups. In group 1 (n=20) acupuncture was applied unilaterally at the Quchi (LI 11) acupoint three times per week for 1 month. In group 2 (controls, n=20) acupuncture was applied at a non-acupoint 2 cm lateral to Quchi (LI 11) three times per week for 1 month. Subjects responded to a pruritus score questionnaire given before and at the end of the 1-month treatment and at a 3-month follow-up. In group 1 pruritus scores before and after acupuncture and at the 3-month follow-up were 38.3±4.3, 17.3±5.5 and 16.5±4.9, and in group 2 (controls) they were 38.3±4.3, 37.5±2 and 37.1±5, respectively. Laboratory tests showed no significant differences between the two groups. Pruritus scores were significantly lower after acupuncture and at the 3-month follow-up.