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FACT
Focus on Alternative and Complementary Therapies

Effect of γ-oryzanol-processed rice on serum total and LDL cholesterol levels – a trial of staple food improvement for borderline people of hypercholesteraemia

Kamei T1,2, Murata K2, Toriumi Y3, Iwata K4
1Shimane Institute of Health Science, 223-7 Enya-cho, Izumo, Japan
2Kanazawa University Graduate School of Medical Science, 13-1 Takaramachi, Kanazawa, Japan
3Shimane University, 89-1 Enya-cho, Izumo, Japan
4Beijing International SOS Clinic, No.1 North Road, Xing Fu San Cun, Chaoyang district, Beijing, China

Objective

The aim of this study was to examine the effect of γ-oryzanol-processed rice on serum cholesterol levels and to discuss the possibility of using this rice as a health-promoting staple food in East Asia.

Materials and methods

After receiving permission from the Committee of Shimane Institute of Health Science, we examined the cholesterol levels of 90 healthy adults who were randomly assigned to take the processed rice enriched with an extract from brown rice that contained γ-oryzanol. For 30 days we directed group A (n = 30) to take processed rice with 7.5 mg of γ-oryzanol per 100 g of rice and group B (n = 30) to take processed rice with half the γ-oryzanol dose of group A. Only control rice (not processed rice) was given to group C (n = 30).

Results

During this single blinded study, total cholesterol levels decreased in group A (P < 0.01) and group B (P < 0.05). LDL cholesterol levels decreased only in group A (P < 0.05).

Conclusion

The γ-oryzanol-processed rice could be effective in preventing arteriosclerosis by reducing total and LDL cholesterol levels. The appropriate dose would be 7.5 mg/100 g. The improvement of staple food using γ-oryzanol processing may be beneficial for people with borderline hypercholesteraemia.

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