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FACT
Focus on Alternative and Complementary Therapies

Treatment of lateral epicondylitis by leeches – a randomised controlled trial

Bäcker M1, Michalsen A1, Cesur Ö1, Afra D1, Rampp T1, Dobos GJ1, Lüdtke R2, Fink M3, Bachmann J4
1Chair of Complementary and Integrative Medicine, University Duisburg-Essen, Kliniken Essen-Mitte, Department of Internal and Integrative Medicine, Am Deimelsberg 34a, D-45276 Essen, Germany
2Karl and Veronica Carstens Foundation, Am Deimelsberg 36, 45276 Essen, Germany
3Department of Physical Therapy, Hannover Medical School, Germany
4Augusta Medical Clinic, Hattingen, Germany

Objective

To test the effectiveness of leech therapy compared to topical diclofenac in lateral epicondylitis.

Materials and methods

Forty patients with lateral epicondylitis of at least 1 month’s duration were randomised to a single treatment with two to four locally applied leeches or a 30-day course with topical diclofenac twice a day. Primary outcome was change of mean pain 7 days after treatment calculated from three scores on a VAS for pain at rest, in motion and during grip. Secondary outcomes were functional disability (DASH questionnaire), physical quality of life (pQoL/SF-36) and grip strength. Patients were examined at days −3, 0, 7 and 45.

Results

Leech therapy reduced the mean pain score significantly more (P = 0.0075) compared to diclofenac at day 7 [leech group: 143.7 (±36.9) to 95.3 (±45.1), diclofenac: 131.6 (±29.6) to 134.7 (±70.7)]. Functional disability showed a significant (P = 0.0007) stronger decrease in the leech group, most prominent after 6 weeks with a DASH decrease from 41.3 (±15.9) to 21.4 (±14.6) and from 35.9 (±13.8) to 31.9 (±15.5) in the diclofenac group. There was a moderate increase in pQoL and grip strength in both groups without any significant group difference. When adjusting for outcome expectation and baseline differences results remained unchanged.

Conclusion

A single course of leech therapy was effective in relieving pain and improving function in the short and intermediate term. Leeches might therefore be considered as a therapeutic option within an integrative therapeutic approach to lateral epicondylitis.

Acknowledgements

The study was funded by the Karl and Veronica Carstens-Foundation, Germany.

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