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AHFS Drug Information

For more than 50 years AHFS Drug Information (AHFS DI) has been the leading source of evidence-based drug information. It addresses critical questions that need objective evidence, and is peer-reviewed by over 500 pharmacists, physicians, and other healthcare professionals.

The work is supported by extensive objective research from primary sources, and compiled without any influence from manufacturers, insurers, regulators or other interested parties.

AHFS DI is published by the American Society of Health-System Pharmacists (ASHP).

How AHFS DI will help you

  • Provides you with detailed, comprehensive clinical data and therapeutic guidelines on all FDA approved drugs and medicines
  • Supports your work by providing you with objective evidence through links to primary literature
  • Offers fast and easy access to evidence-based data on labeled and unlabeled drug use


All the content is revalidated, revised, and updated on a regular basis. This process involves both scheduled, in-depth revision on each monograph, and updates in reaction to new information as it arrives. All monographs and updates are peer-reviewed, and supported by references to primary research and literature.

Who should use this resource?

  • Pharmacists
  • Clinicians
  • Healthcare professionals

Key coverage includes:

  • Uses included in the labeling approved by the US Food and Drug Administration and uses that are unlabeled but well-established in the scientific literature
  • Over 1,200 monographs on over 50,000 drug products
  • Structured, codified, evidence-based determinations for off-label cancer uses
  • 84,000 references linked to more than 600,000 content elements
  • 50,000 references with hyperlinks to PubMed citations in the National Library of Medicine's database for access to full-text of articles
  • Drug interactions, cautions, and toxicity alerts
  • Detailed information on dosage and methods of administration
  • Thorough examination of well-established laboratory and test inferences

Content includes:

  • Mechanism of action, spectrum, and resistance
  • US brand and generic names
  • Synonyms
  • Therapeutic class
  • Uses - labeled and unlabeled
  • Dosage and administration
  • Cautions
  • Drug interactions
  • Pharmacology
  • Laboratory test interferences
  • Pharmacokinetics
  • Chemistry and stability
  • Preparations
  • References

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