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15-11-2017: AHFS Drug Information November 2017 update

This update contains 5 new monographs and 31 revised monographs.

New monographs: Gemtuzumab; Deutetrabenazine; DAUNOrubicin and Cytarabine; Selenious Acid; Inotuzumab.

Revised monographs: levETIRAcetam; Bivalirudin; Caspofungin; Levofloxacin; Tenofovir Disoproxil Fumarate; Micafungin; Anidulafungin; Telavancin; Saxagliptin; Vandetanib; Pembrolizumab; Osimertinib; Obeticholic Acid; Sodium Polystyrene Sulfonate; Methadone; Ephedrine; Estrogens, Conjugated; Dopamine; Beta Carotene; Epinephrine; Dipyridamole; Antimuscarinics/Antispasmodics General Statement; Naltrexone; Buprenorphine; Risperidone; Abciximab; Bupropion; Ticlopidine; Metformin; Eptifibatide; Tirofiban.


12-10-2017: AHFS Drug Information October 2017 update

This update contains 4 new monographs and 44 revised monographs.

New monographs: Sofosbuvir, Velpatasvir, And Voxilaprevir; Enasidenib; Neratinib; Glecaprevir And Pibrentasvir.

Revised monographs: Valrubicin; Triptorelin; Goserelin; Fulvestrant; Estramustine; Teriparatide; Cinacalcet; SUNItinib; PONATinib; Belinostat; Ramucirumab; Pembrolizumab; Idelalisib; Nivolumab; Olaparib; Ibrutinib; Lenvatinib; Parathyroid Hormone; Lifitegrast; Obeticholic Acid; Olaratumab; Etelcalcetide; Abaloparatide; Floxuridine; Thioguanine; Mechlorethamine; Phenylephrine; Mitotane; Dopamine; Vasopressin; Norepinephrine; Calcitonin; Epinephrine; Thiotepa; Corticosteroids General Statement; Antineoplastic Agents General Statement; CISplatin; Streptozocin; Leuprolide; Teniposide; Nilutamide; Flutamide; Toremifene; PACLitaxel.


13-9-2017: AHFS Drug Information September 2017 update

This update contains 6 new monographs and 12 revised monographs.

New monographs: Trientine; Delafloxacin; Betrixaban; Naltrexone And Bupropion; Guselkumab; L-Glutamine.

Revised monographs: Infliximab, Infliximab-dyyb; Emtricitabine; Azilsartan; Linaclotide; Cholic Acid; Olaratumab; Cholera Vaccine Live Oral; Plecanatide; Typhoid Vaccine; Yellow Fever Vaccine; Irinotecan; Antiretroviral Agents General Statement.


8-8-2017: AHFS Drug Information August 2017 update

This update contains 4 new monographs and 17 revised monographs.

New monographs: Bezlotoxumab; Sarilumab; Becaplermin; Prasterone.

Revised monographs: Atorvastatin; HMG-CoA Reductase Inhibitors General Statement; Ezetimibe; Rosuvastatin; Golimumab; Iloperidone; Pitavastatin; Brexpiprazole; Cariprazine; Magnesium Sulfate; Acetylcholine; Anticonvulsants General Statement; Barbiturates General Statement; Lovastatin; Pravastatin; Simvastatin; Fluvastatin.


12-7-2017: AHFS Drug Information July 2017 update

This update contains 13 new monographs and 36 revised monographs.

New monographs: Elotuzumab; Metreleptin; Tenofovir Alafenamide; Deutetrabenazine; Niraparib; Valbenazine; Durvalumab; Brigatinib; Midostaurin; Cerliponase Alfa; Abaloparatide; Safinamide; Edaravone.

Revised monographs: levETIRAcetam; Lopinavir and Ritonavir; Levofloxacin; Eprosartan; Telmisartan; Olmesartan; Propofol; Etomidate; Teriparatide; Gatifloxacin; Moxifloxacin; Atazanavir; Fosamprenavir; Darunavir; Varenicline; Raltegravir; Besifloxacin; Azilsartan; Canagliflozin; Dolutegravir; LORazepam; Methohexital; Naloxone; Ephedrine; PENTobarbital; Midazolam; Esmolol; Losartan; niCARdipine; Bupropion; Saquinavir; Topiramate; Valsartan; Irbesartan; Efavirenz; Abacavir.


14-6-2017: AHFS Drug Information June 2017 update

This update contains 7 new monographs and 19 revised monographs.

New monographs: Lumacaftor and Ivacaftor; Ocrelizumab; Dupilumab; Etelcalcetide; Naldemedine; Urdine Triacetate; Deutetrabenazine.

Revised monographs: Levetiracetam; Oxcarbazepine; Saxagliptin; Alogliptin; Nitroglycerin; Sulindac; Codeine; Tromethamine; Lidocaine; Boric Acid; Antimuscarinics/Antispasmodics General Statement; Atropine; Enoxaparin; Tramadol; Metformin; Topiramate; Tiagabine; Paroxetine; Capecitabine.


9-5-2017: AHFS Drug Information May 2017 update

This update contains 15 new monographs and 83 revised monographs, including MedWatch Alerts for 1 monograph.

New monographs: Sebelipase Alfa; Reslizumab; Lesinurad; Daclizumab; Eliglustat; Von Willebrand Factor (recombinant); Oxymetazoline; Deflazacort; Cholera Vaccine Live Oral; Plecanatide; Brodalumab; Anthrax Immune Globulin IV (Human); Telotristat; Ribociclib and Avelumab.

Revised monographs: Triptorelin; Pantoprazole; Esomeprazole; Clopidogrel; Interferon Alfa; Oxaliplatin; ARIPiprazole; Miglustat; Daptomycin; Cetuximab; Bevacizumab; rifAXIMin; Imiglucerase; Galsulfase; Bismuth Salts; Tetrabenazine; Dexlansoprazole; Lacosamide; PAZOPanib; Fingolimod; Lurasidone; Collagenase Clostridium Histolyticum; Velaglucerase Alfa; Ingenol Mebutate; Taliglucerase Alfa; Teduglutide; Canagliflozin; Ceritinib; Albiglutide; Dapagliflozin; Empagliflozin; Eluxadoline; Cobimetinib; Necitumumab; Trabectedin; Brivaracetam; Brexpiprazole; Cariprazine; Mefenamic Acid; HYDROcodone; PHENobarbital; Antihemophilic Factor (Human); chlordiazePOXIDE; oxyCODONE; Methadone; azaTHIOprine; fluPHENAZine; Haloperidol; metroNIDAZOLE; Diazoxide; ePHEDrine; Deferoxamine; Promethazine; DAUNOrubicin; quiNIDine; PENTobarbital; Potassium Iodide; fentaNYL; Benzonatate; acetaZOLAMIDE; prednisoLONE; methylPREDNISolone; Betamethasone; vinCRIStine; PHENobarbital; Colistimethate; Metoprolol; hydrOXYzine; prednisoloneLONE; Corticosteroids General Statement; Cathartics and Laxatives General Statement; Diclofenac; Ofloxacin; Omeprazole; Antihemophilic Factor (Recombinant); SUMAtriptan; OLANZapine; Letrozole; Citalopram; Abacavir; RABEprazole; Quinupristin/Dalfopristin and Oseltamivir.


12-4-2017: AHFS Drug Information April 2017 update

This update contains 7 new monographs and 36 revised monographs.

New monographs: Antihemophilic Factor (Recombinant), Fc fusion protein; Asfotase Alfa; Crisaborole; Calcifediol; Meningococcal Group B Vaccine; Factor IX (Recombinant), Fc fusion protein; Factor XIII A-Subunit (Recombinant).

Revised monographs: Oxaliplatin; Paliperidone; Nebivolol; Factor XIII; Ivabradine Hydrochloride; Fenoprofen; Amiloride; Antihemophilic Factor (Human); Meclofenamate; Triamterene; Chlorthalidone; Metolazone; Propranolol; Nadolol; Captopril; Metoprolol; dilTIAZem; Timolol; Atenolol; Pindolol; Indapamide; Labetalol; Antivenin (Micrurus fulvius) (Equine); Enalapril; Acebutolol; Fosinopril; Quinapril; Bisoprolol; Betaxolol; Antihemophilic Factor (Recombinant); Moexipril; Trandolapril; Carvedilol; Capecitabine; Orlistat; Perindopril.


14-3-2017: AHFS Drug Information March 2017 update

This update contains 8 new monographs and 48 revised monographs, including MedWatch Alerts for 2 monographs.

New monographs: Atezolizumab; Antihemophilic Factor (Recombinant), Porcine Sequence; Ivabradine Hydrochloride; Avanafil; Brexpiprazole; Patiromer; Ixekizumab; Sofosbuvir and Velpatasvir.

Revised monographs: Alosetron; Dolasetron; Nesiritide; Eplerenone; Aripiprazole; Flurbiprofen; Palonosetron; Factor Ix (Recombinant); Tapentadol; Tolmetin; Hydrocodone; Sodium Bicarbonate; Hydromorphone; Factor Ix, Factor Ix Complex (Human); Sodium Polystyrene Sulfonate; Oxycodone; Sodium Nitroprusside; Hydralazine; Digoxin; Pentazocine; Magnesium Sulfate; Chlorothiazide; Nitroglycerin; Isosorbide; Hydrochlorothiazide; Spironolactone; Butorphanol; Nalbuphine; Calcium Salts; Ethacrynic Acid; Furosemide; Opiates GS; Thiazides GS; Nitrates &Nitrites GS; Cardiac Glycosides GS; Diflunisal; Bumetanide; Sufentanil; Ketoprofen; Buprenorphine; Clozapine; Benazepril; Ondansetron; Ramipril; Lisinopril; Torsemide; Tramadol; Meningococcal Vaccine Groups A, C, Y, And W-135.


15-2-2017: AHFS Drug Information February 2017 update

This update contains 4 new monographs and 19 revised monographs, including MedWatch Alerts for 9 monographs.

New monographs: Netupitant/Palonosetron; Sugammadex; Rucaparib; Nusinersen.

Revised monographs: Propofol; Etomidate; Aprepitant/Fosaprepitant; Varenicline; Vigabatrin; Lorazepam; Chlordiazepoxide; Methohexital; Loperamide; Pentobarbital; Hydrocodone; Butorphanol; Opium Preparations; Erythromycins General Statement; Midazolam; Oxaprozin; Granisetron; Bupropion; Pioglitazone.


10-1-2017: AHFS Drug Information January 2017 update

This update contains 6 new monograph and 49 revised monographs.

New monographs: Idarucizumab; Sacubitril and Valsartan; Brivaracetam; Cariprazine; Pimavanserin; Tenofovir Alafenamide.

Revised monographs: Meloxicam; Reteplase; Mexiletine; Adenosine; Posaconazole; Dabigatran; Nintedanib; Elbasvir and Grazoprevir; Trifluridine and Tipiracil; Netupitant and Palonosetron; Lesinurad; Indomethacin; Naproxen; Codeine; Meperidine; Oxymorphone; Morphine; Methadone; Ibuprofen; Naloxone; Lidocaine; Quinidine; Fentanyl; Propranolol; Betamethasone; Metoprolol; Antituberculosis Agents General Statement; Benzodiazepines General Statement; Aminoglycosides General Statement; Cardiac Glycosides General Statement; Diltiazem; Verapamil; Atenolol; Piroxicam; Flecainide; Amiodarone; Esmolol; Diclofenac; Ketorolac; Etodolac; Nabumetone; Ramipril; Filgrastim, Filgrastim-sndz, Tbo-filgrastim; Oxaprozin; Sotalol; Ibutilide; Olanzapine; Propafenone; Celecoxib.


14-12-2016: AHFS Drug Information December 2016 update

This update contains 12 new monographs and 48 revised monographs, including MedWatch Alerts for 12 monographs.

New monographs: Alectinib; Daratumumab; Ixazomib Citrate; Osimertinib; Palbociclib; Sonidegib; Trabectedin; Trifluridine and Tipiracil; Venetoclax; Dichlorphenamide; Olaratumab; Bezlotoxumab.

Revised monographs: Clopidogrel; Tenofovir Disoproxil Fumarate; Influenza Vaccine Live Intranasal; Emtricitabine; Rifaximin; Oxandrolone; Fidaxomicin; Vemurafenib; Icatibant; Brentuximab; Deferiprone; Ticagrelor; Carfilzomib; Bosutinib; Influenza Vaccine Recombinant; Carglumic Acid; Dabrafenib; Trametinib Dimethyl Sulfoxide; Simeprevir; Sofosbuvir; Cysteamine; Vortioxetine; Tasimelteon; Perampanel; Ledipasvir and Sofosbuvir; Droxidopa; Ombitasvir, Paritaprevir, and Ritonavir with Dasabuvir Sodium; Panobinostat; Daclatasvir; Ombitasvir/Paritaprevir/Ritonavir; Elbasvir and Grazoprevir; Raxibacumab; Phentolamine; Trifluridine; Nitroglycerin; Procainamide; Disopyramide; Danazol; Testosterone; Methyltestosterone; Fluoxymesterone; Epinephrine; Dobutamine; Nitrates and Nitrites General Statement; Aztreonam; Alteplase; Influenza Virus Vaccine Inactivated; Antiretroviral Agents General Statement.


7-11-2016: AHFS Drug Information November 2016 update

This update contains 53 new monographs and 17 revised monographs.

New monographs: Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide; Raxibacumab; Alectinib; Atezolizumab; Daratumumab; Elotuzumab; Ixazomib; Necitumumab; Osimertinib; Palbociclib; Sonidegib; Trabectedin; Trifluridine and Tipiracil; Venetoclax; Defibrotide Sodium; Antihemophilic Factor (recombinant), Fc Fusion Protein; Antihemophilic Factor (Recombinant), Porcine Sequence; Coagulation Factor IX (Recombinant, Human); Coagulation Factor X Human; Idarucizumab; Ivabradine Hydrochloride; Avanafil; Sacubitril and Valsartan; Brivaracetam; Brexpiprazole; Cariprazine; Pimavanserin; Patiromer; Asfotase Alfa; Sebelipase Alfa; Mepolizumab; Reslizumab; Lumacaftor and Ivacaftor; Selexipag; Lifitegrast; Netupitant and Palonosetron; Rolapitant; Cholic Acid; Obeticholic Acid; Lixisenatide; Insulin Degludec; Metreleptin; Obiltoxaximab; Ixekizumab; Sugammadex; Lesinurad; Daclizumab; Cobicistat; Deoxycholic Acid; Dichlorphenamide; Eliglustat; Elvitegravir; Eteplirsen.

Revised monographs: Moxifloxacin; Aprepitant/Fosaprepitant; Gemifloxacin; Bevacizumab; Sunitinib; Ceftaroline; Rilpivirine; Daunorubicin; Acetazolamide; Ketoconazole; Carbonic Anhydrase Inhibitors General Statement; Imipenem and Cilastatin; Ciprofloxacin; Apraclonidine; Fluconazole; Ofloxacin; Levofloxacin.


11-10-2016: AHFS Drug Information October 2016 update

This update contains 1 new monograph and 38 revised monographs, including MedWatch Alerts for 28 monographs.

New monograph: Elvitegravir.

Revised monographs: Tenecteplase; Milrinone; Remifentanil; Tapentadol; Clobazam; Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir DF; Hydrocodone; Hydromorphone; Diazepam; Oxazepam; Flurazepam; Clorazepate; Lorazepam; Codeine (Analgesic); Chlordiazepoxide; Physostigmine; Meperidine; Oxymorphone; Oxycodon; Morphine; Methadone; Terbutaline; Clonazepam; Pentazocine; Codeine (Antitussive); Hydrocodone; Fentanyl; Butorphanol; Dipyridamole; Charcoal, Activated; Phenothiazines General Statement; Alprazolam; Temazepam; Triazolam; Buprenorphine; Quazepam; Estazolam; Tramadol.

MedWatch alerts: Remifentanil; Tapentadol; Hydrocodone; Hydromorphone; Codeine; Meperidine; Oxymorphone; Oxycodone; Morphine; Methadone; Fentanyl; Tramadol; Pentazocine; Butorphanol; Buprenorphine; Clobazam; Clonazepam; Diazepam; Oxazepam; Flurazepam; Clorazepate; Lorazepam; Chlordiazepoxide; Alprazolam; Temazepam; Triazolam; Quazepam; Estazolam.


14-9-2016: AHFS Drug Information September 2016 update

This update contains 4 new monographs and 15 revised monographs, including MedWatch Alerts for 5 monographs.

New monographs: Vorapaxar; Elbasvir and Grazoprevir; Cobimetinib; Flibanserin.

Revised monographs: Moxifloxacin; Tizanidine; Gemifloxacin; Vemurafenib; Asparaginase (Erwinia chrysanthemi); Dabrafenib; Trametinib Dimethyl Sulfoxide; Nivolumab; Benzocaine; Fentanyl; Hydrocortisone; Ciprofloxacin; Ofloxacin; Pegaspargase; Levofloxacin.

MedWatch alerts: Moxifloxacin; Ofloxacin; Ciprofloxacin; Levofloxacin; Gemifloxacin.


10-8-2016: AHFS Drug Information August 2016 update

This update contains 2 new monographs and 17 revised monographs, including MedWatch Alerts for 5 monographs.

New monographs: Daclatasvir; Ombitasvir, Paritaprevir, and Ritonavir.

Revised monographs: Bevacizumab; Ranibizumab; Bendamustine; Canagliflozin; Simeprevir; Dapagliflozin; Ledipasvir and Sofosbuvir; Ombitasvir, Paritaprevir, and Ritonavir with Dasabuvir Sodium; Ephedrine; Loperamide; Dopamine; Isoproterenol; Norepinephrine; Aspirin; Tramadol; Sumatriptan; Rituximab.

MedWatch alerts: Canagliflozin; Dapagliflozin; Aspirin; Sumatriptan; Loperamide.


13-7-2016: AHFS Drug Information July 2016 update

This update contains 4 new monographs and 18 revised monographs, including MedWatch Alerts for 8 monographs.

New monographs: Talimogene Laherparepvec; Elosulfase Alfa; Alirocumab; Evolocumab.

Revised monographs: Moxifloxacin; Dofetilide; Mifepristone; Gemifloxacin; Emtricitabine; Posaconazole; Dronedarone; Apixaban; Tofacitinib; Ezogabine; Canagliflozin; Ketoconazole; Ciprofloxacin; Ofloxacin; Olanzapine; Levofloxacin; Rosiglitazone; Quinupristin/Dalfopristin.

MedWatch alerts: Moxifloxacin; Ofloxacin; Ciprofloxacin; Levofloxacin; Gemifloxacin; Ketoconazole; Canagliflozin; Olanzapine.


15-6-2016: AHFS Drug Information June 2016 update

This update contains 1 new monograph and 11 revised monographs, including MedWatch Alerts for 5 monographs.

New monographs: Ganciclovir.

Revised monographs: Aripiprazole; Ticagrelor; Vortioxetine; Clonidine; Trifluridine; Bacitracin; Nortriptyline; Nicotine; Fluconazole; Bupropion; Metformin.

MedWatch alerts: Metformin; Fluconazole; Aripiprazole; Ticagrelor; Vortioxetine.


11-5-2016: AHFS Drug Information May 2016 update

This update contains 2 new monographs and 49 revised monographs, including MedWatch Alerts for 19 monographs and a REMS update for 8 monographs.

New monographs: Eluxadoline; Dinutuximab.

Revised monographs: Alosetron; Linezolid; Alemtuzumab; Sodium Oxybate; Remifentanil; Tetrabenazine; Eltrombopag; Everolimus; Dronedarone; Tapentadol; Ofatumumab; Telavancin; Alglucosidase Alfa; Saxagliptin; Ipilimumab; Aflibercept; Carfilzomib; Ziv-aflibercept; Bosutinib; Enzalutamide; Regorafenib; Ado-Trastuzumab Emtansine; Pomalidomide; Alogliptin; Afatinib; Obinutuzumab; Alemtuzumab; Naproxen; Hydrocodone; Hydromorphone; Codeine; Meperidine; Oxymorphone; Oxycodone; Morphine; Methadone; Pentazocine; Nitroglycerin; Fentanyl; Progestins; Butorphanol; Pancrelipase; Opiate Agonists General Statement; Nitrates and Nitrites General Statement; Sufentanil Citrate; Buprenorphine; Interferon Alfa; Tramadol; Vinorelbine.

MedWatch alerts: Buprenorphine, Butorphanol, Codeine, Fentanyl, Hydrocodone, Hydromorphone, Meperidine, Methadone, Morphine, Oxycodone, Oxymorphone, Pentazocine, Remifentanil, Sufentanil, Tapentadol, Tramadol, Opiates GS, Saxagliptin, Alogliptin.

REMS updates: Everolimus, Ipilimumab, Eltrombopag olamine, Dronedarone hydrochloride, Sodium oxybate, Tetrabenazine, Alglucosidase alfa, Pancrelipase.


13-4-2016: AHFS Drug Information April 2016 update

This update contains 3 new monographs and 28 revised monographs.

New monographs: Blinatumomab; Naloxegol; Miltefosine.

Revised monographs: Entacapone; Ziprasidone; Olmesartan; Aripiprazole; Omalizumab; Daptomycin; Raltegravir; Methylnaltrexone; Apixaban; Dolutegravir; Bazedoxifene; Chlorothiazide; Chlorthalidone; Estrogens, Conjugated; Salicylic Acid; Estrogens General Statement; Diltiazem; Nifedipine; Indapamide; Ribavirin; Zidovudine; Interferon Alfa; Terbinafine; Poliovirus Vaccine Inactivated; Moexipril; Ticlopidine; Olanzapine; Penciclovir.


8-3-2016: AHFS Drug Information March 2016 update

This update contains 1 new monograph and 17 revised monographs.

New monograph: C1-Esterase Inhibitor (Recombinant).

Revised monographs: Alemtuzumab; Atazanavir; Cinacalcet; Darunavir; Varenicline; Fibrin Sealant; Acetaminophen; Dextromethorphan; Guaifenesin; Cyproheptadine; Clemastine; Chlorpheniramine; Brompheniramine; Succinylcholine; Benzonatate; Clotrimazole; Carbinoxamine.

Revised monographs regarding earlier Medwatch alerts: Celecoxib; Diclofenac; Diflunisal; Etodolac; Fenoprofen; Flurbiprofen; Ibuprofen; Indomethacin; Ketoprofen; Ketorolac; Mefenamic Acid; Meloxicam; Nabumetone; Naproxen; Oxaprozin; Piroxicam; Sulindac; Tolmetin; Tramadol; Clozapine; Ombitasvir, Paritaprevir, and Ritonavir with Dasabuvir; Codeine; Sodium Polystyrene Sulfonate; Ingenol Mebutate; Entacapone.


10-2-2016: AHFS Drug Information February 2016 update

This update contains 6 new monographs and 28 revised monographs, including MedWatch Alerts for 3 monographs.

New monographs: Pentosan, Brimonidine (Topical), Bazedoxifene, Empagliflozin, Parathyroid Hormone, Peginterferon Beta-1a.

Revised monographs: Etanercept, Brimonidine (EENT), Epinastine, Exenatide, Human Papillomavirus Vaccine, Ranibizumab, Posaconazole, Sitagliptin, Tocilizumab, Liraglutide, Fingolimod, Saxagliptin, Linagliptin, Alogliptin, Canagliflozin, Albiglutide, Dapagliflozin, Umeclidinium, Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed (DTaP/Tdap), Diphtheria and Tetanus Toxoids, Benzocaine, Levothyroxine, Benzocaine, Pneumococcal Vaccine, Testosterone, Methyltestosterone, Thyroid Agents General Statement, Octreotide.

MedWatch Alerts: Empagliflozin, Canagliflozin, Dapagliflozin.


13-1-2016: AHFS Drug Information January 2016 update

This update contains 5 new monographs and 34 revised monographs, including MedWatch Alerts for 1 monograph.

New monographs: Umeclidinium, Cangrelor, Edoxaban Tosylate, Nintedanib, Pirfenidone.

Revised monographs: Clopidogrel, Dexmethylphenidate, Telmisartan, Olmesartan, Propofol, Brimonidine, Aliskiren, Ferumoxytol, Prasugrel, Dabigatran, Rivaroxaban, Ticagrelor, Apixaban, Ezogabine, Vortioxetine, Methylphenidate, Warfarin, Hydrochlorothiazide, Aspirin, Naltrexone, Natural Penicillins General Statement, Ribavirin, Amiodarone, Amlodipine, Gabapentin, Risperidone, Abciximab, Poliovirus Vaccine Inactivated, Ticlopidine, Olanzapine, Valsartan, Eptifibatide, Perindopril, Tirofiban.

MedWatch Alerts: Clopidogrel.


8-12-2015: AHFS Drug Information December 2015 update

This update contains 6 new monographs and 25 revised monographs, including MedWatch Alerts for 3 monographs.

New monographs: Ceftazidime and Avibactam Sodium; Ceftolozane Sulfate and Tazobactam Sodium; Panobinostat; Lenvatinib; Siltuximab; Olodaterol.

Revised monographs: Entacapone; Peginterferon Alfa; Influenza Vaccine Live Intranasal; Bendamustine; Influenza Vaccine Recombinant; Vilanterol; Ombitasvir, Paritaprevir, and Ritonavir with Dasabuvir Sodium; Sodium Polystyrene Sulfonate; Sulfadiazine; Ephedrine; Triprolidine; Doxylamine; Diphenhydramine; Pseudoephedrine; Sulfonamides General Statement; Antihistamines General Statement; Cephalosporins General Statement; Methscopolamine; Ribavirin; Ofloxacin; Influenza Virus Vaccine Inactivated; Midodrine; Fexofenadine; Loratadine; Antiretroviral Agents General Statement.

MedWatch Alerts: Entacapone; Ombitasvir, Paritaprevir, and Ritonavir with Dasabuvir Sodium; Sodium polystyrene sulfonate.


12-11-2015: AHFS Drug Information November 2015 update

This update contains 4 new monographs and 19 revised monographs, including MedWatch Alerts for 3 monographs.

New monographs: Isavuconazonium; Ibrutinib; Ferric Citrate; Sucroferric Oxyhydroxide.

Revised monographs: Moxifloxacin; Triamcinolone; Mometasone (EENT); Tegaserod; Mometasone (Hormones and Synthetic Substitutes); Canagliflozin; Neostigmine; Phenylephrine; Aminohippurate; Miotics General Statement; Mometasone (Topical); Clozapine; Tramadol; Levofloxacin; Rituximab; Citalopram; Anti-infective Agents; Antineoplastic Agents; Electrolytic, Caloric, and Water Balance.

MedWatch Alerts: Canagliflozin; Clozapine; Tramadol.


14-10-2015: AHFS Drug Information October 2015 update

This update contains 3 new monographs and 38 revised monographs, including MedWatch Alerts for 29 monographs.

New monographs: Peramivir; Suvorexant; Olaparib.

Revised monographs: Meloxicam; Flurbiprofen; Sitagliptin; Vigabatrin; Fingolimod; Saxagliptin; Linagliptin; Ticagrelor; Ingenol Mebutate; Regorafenib; Dabrafenib; Trametinib Dimethyl Sulfoxide; Alogliptin; Dimethyl Fumarate; Vortioxetine; Ledipasvir and Sofosbuvir; Secukinumab; Fenoprofen; Indomethacin; Mefenamic Acid; Naproxen; Tolmetin; Sulindac; Ibuprofen; Diazoxide; Benzocaine; Codeine; Atropine; Diflunisal; Piroxicam; Ketoprofen; Diclofenac; Ketorolac; Etodolac; Nabumetone; Oxaprozin; Topotecan; Celecoxib.

MedWatch Alerts: Meloxicam; Flurbiprofen; Sitagliptin; Fingolimod; Saxagliptin; Linagliptin; Ticagrelor; Ingenol Mebutate; Alogliptin; Vortioxetine; Fenoprofen; Indomethacin; Mefenamic Acid; Naproxen; Tolmetin; Sulindac; Ibuprofen; Codeine; Diazoxide; Benzocaine; Diflunisal; Piroxicam; Ketoprofen; Diclofenac; Ketorolac; Etodolac; Nabumetone; Oxaprozin; Celecoxib.


9-9-2015: AHFS Drug Information September 2015 update

This update contains 3 new monographs and 10 revised monographs.

New monographs: Droxidopa; Secukinumab; Ombitasvir, Paritaprevir, and Ritonavir with Dasabuvir Sodium.

Revised monographs: Tocilizumab; Vemurafenib; Sulfonamides General Statement; Glycopyrrolate; Verapamil; Cisplatin; Flecainide; Ciprofloxacin; Propafenone; Paclitaxel.


12-8-2015: AHFS Drug Information August 2015 update

This update contains 3 new monographs and 17 revised monographs, including MedWatch Alerts for 1 monograph and a REMS update for 1 monograph.

New monographs: Ledipasvir and Sofosbuvir, Dulaglutide, Nivolumab.

Revised monographs: Infliximab, Mycophenolate, Adenosine, Antithrombin alfa, Regadenoson, Rivaroxaban, Ezogabine, Simeprevir, Sofosbuvir, Hydrocodone, Aminocaproic Acid, Protamine, Heparin, Opiate Agonists General Statement, Alteplase, Japanese Encephalitis Vaccine, Docetaxel.

MedWatch Alerts: Ezogabine.

REMS update: Hydrocodone.


15-7-2015: AHFS Drug Information July 2015 update

This update contains 5 new monographs and 5 revised monographs, including MedWatch alerts for 2 monographs.

New monographs: Botulism Antitoxin (Equine), Adenovirus Vaccine Live Oral, Vedolizumab, Pembrolizumab, Idelalisib.

Revised monographs: Milnacipran, Canagliflozin, Levomilnacipran, Dapagliflozin, Pneumococcal Vaccine.

MedWatch alerts: Canagliflozin, Dapagliflozin.


10-6-2015: AHFS Drug Information June 2015 update

This update contains 5 new monographs and 7 revised monographs.

New monographs: Eslicarbazepine, Ferric Carboxymaltose, AbobotulinumtoxinA, IncobotulinumtoxinA, RimabotulinumtoxinB.

Revised monographs: Cetuximab, OnabotulinumtoxinA, Sunitinib, Anticonvulsants General Statement, Fosinopril, Moexipril, Olanzapine.


12-5-2015: AHFS Drug Information May 2015 update

This update contains 5 new monographs and 10 revised monographs, including MedWatch alerts for 5 monographs.

New monographs: Mechlorethamine, Ramucirumab, Dalbavancin, Oritavancin, Tedizolid.

Revised monographs: Mifepristone, Teriparatide, Ferumoxytol, Simeprevir, Sofosbuvir, Clorazepate, Mechlorethamine, Amiodarone, Olanzapine, Oseltamivir.

Medwatch alerts: Ferumoxytol, Simeprevir, Sofosbuvir, Amiodarone, Olanzapine.


15-4-2015: AHFS Drug Information April 2015 update

This update contains 4 new monographs and 8 revised monographs, including MedWatch alerts for 3 monographs.

New monographs: Belinostat, Perampanel, Apremilast, Vilanterol.

Revised monographs: Clopidogrel, Varenicline, Bendamustine, Prasugrel, Lurasidone, Brentuximab, Testosterone, Cefazolin.

Medwatch alerts: Bendamustine, Varenicline, Testosterone.


11-3-2015: AHFS Drug Information March 2015 update

This update contains 7 new monographs and 83 revised monographs. Updated information from HIV and hypertension therapeutic guidelines has been added, and preparations in the opiate monographs updated. REMS information has been updated for clonazepam.

New monographs: Vortioxetine, Albiglutide, Dapagliflozin, Nitroglycerin, Luliconazole, Efinaconazole, Tavaborole.

Revised monographs: Delavirdine, Enfuvirtide, Tipranavir, Maraviroc, Didanosine, Stavudine, Saquinavir, Indinavir, Ritonavir, Nelfinavir, Eprosartan, Telmisartan, Eplerenone, Nebivolol, Guanfacine, Azilsartan, Sodium Nitroprusside, Methyldopa, Clonidine, Prazosin, Hydralazine, Isosorbide, Propranolol, Minoxidil, Nadolol, Metoprolol, Rauwolfia Alkaloids, Nitrates and Nitrites General Statement, Timolol, Atenolol, Pindolol, Labetalol, Acebutolol, Esmolol, Felodipine, Fosinopril, Quinapril, Lisinopril, Bisoprolol, Doxazosin, Terazosin, Betaxolol, Isradipine, Losartan, Moexipril, Trandolapril, Carvedilol, Perindopril, Tapentadol, Acetaminophen, Hydrocodone, Codeine, Oxycodone, Ibuprofen, Clonazepam, Pentazocine, Aspirin, Opiate Agonists General Statement, Tramadol, Amiloride, Triamterene, Chlorothiazide, Chlorthalidone, Metolazone, Methyclothiazide, Hydrochlorothiazide, Bendroflumethiazide, Spironolactone, Ethacrynic Acid, Furosemide, Bumetanide, Indapamide, Torsemide, Hydrocodone, Canagliflozin, Diazoxide, Dexamethasone, Hydrocortisone, Methylprednisolone, Metformin, Pioglitazone, Rosiglitazone, Antivenin (Latrodectus mactans) (Equine).

Discontinued monographs: Tositumomab, Abarelix, Dextran 70, Urokinase, Tacrine.


11-2-2015: AHFS Drug Information February 2015 update

This update contains 1 new monograph and 29 revised monographs, including a MedWatch alert for 1 monograph. REMS information has also been updated.

New monograph: Tasimelteon.

Revised monographs: Eszopiclone, Liraglutide, Acetaminophen, Hydrocodone (Analgesic), Codeine (Analgesic), Oxycodone, Haloperidol, Naloxone, Pentazocine, Codeine (Antitussive), Hydrocodone (Antitussive), Triamcinolone, Betamethasone, Captopril, Aspirin, Opiate Agonists General Statement, Thiazides General Statement, Corticosteroids General Statement, Antineoplastic Agents General Statement, Salicylates General Statement, Enalapril, Buprenorphine, Benazepril, Ramipril, Simvastatin, Filgrastim, Tbo-filgrastim, Nisoldipine, Glimepiride, Immunobiologic Agents Available from the CDC.

MedWatch alert: Ziprasidone.


14-1-2015: AHFS Drug Information January 2015 update

This update contains 4 new monographs and 52 revised monographs. REMS information has also been updated.

New monographs: Simeprevir, Ceritinib, Lomitapide, Mipomersen.

Revised monographs: Atorvastatin, HMG-CoA Reductase Inhibitors General Statement, Fenofibrate, Colesevelam, Clopidogrel, Fondaparinux, Candesartan, Olmesartan, Ezetimibe, Teriparatide, Rosuvastatin, Adenosine, Mometasone, Omega-3-acid Ethyl Esters, Alvimopan, Everolimus, Prasugrel, Pitavastatin, Dabigatran, Rivaroxaban, Icosapent Ethyl, Apixaban, Dimethyl Fumarate, Albuterol/Levalbuterol, Colestipol, Spectinomycin, Warfarin, Cyclobenzaprine, Niacin, Bisacodyl, Cholestyramine, Testosterone, Pancrelipase, Aspirin, Antihistamines General Statement, Diltiazem, Nifedipine, Verapamil, Metoclopramide, Gemfibrozil, Ribavirin, Zidovudine, Lovastatin, Pravastatin, Amlodipine, Lisinopril, Enoxaparin, Fluvastatin, Nicardipine, Dalteparin, Valsartan, Irbesartan.


10-12-2014: AHFS Drug Information December 2014 update

This update contains 1 new monograph and 35 revised monographs. REMS information has also been updated.

New monograph: Peginterferon Alfa (Antineoplastic Agents).

Revised monographs: Nevirapine, Levofloxacin, Sacrosidase, Peginterferon Alfa (Anti-infective Agents), Interferon Alfa (Anti-infective Agents), Tenofovir, Budesonide, Moxifloxacin, Influenza Vaccine Live Intranasal, Omalizumab, Atazanavir, Emtricitabine, Memantine, Fosamprenavir, Ramelteon, Etravirine, Alglucosidase Alfa, Collagenase Clostridium Histolyticum, Rilpivirine, Influenza Vaccine Recombinant, Elvitegravir and Cobicistat, Dolutegravir, Oxybutynin, Cefoxitin, Pentamidine, Ribavirin, Zidovudine, Interferon Alfa (Antineoplastic Agents), Influenza Virus Vaccine Inactivated, Lamivudine, Anti-infectives Available from the CDC, Donepezil, Antiretroviral Agents General Statement, Efavirenz, Abacavir.


12-11-2014: AHFS Drug Information November 2014 update

This update contains 1 new monograph and 43 revised monographs, including a MedWatch alert for 1 monograph. REMS information has also been updated.

New monograph: Cysteamine.

Revised monographs: Lopinavir and Ritonavir, Zonisamide, Fluticasone, Oxcarbazepine, Omalizumab, Tadalafil, Telithromycin, Ramelteon, Pregabalin, Insulin Detemir, Telbivudine, Doripenem, Tetrabenazine, Milnacipran, Rufinamide, Tapentadol, Telavancin, Lacosamide, Armodafinil, Vilazodone, Trazodone, Primidone, Methsuximide, Carbamazepine, Ethosuximide, Ethotoin, Doxepin, Saline Laxatives, Bisacodyl, Cathartics and Laxatives General Statement, Naltrexone, Cefotetan, Diclofenac, Fluoxetine, Venlafaxine, Lamotrigine, Bupropion, Topiramate, Tiagabine, Quetiapine, Paclitaxel, Sildenafil, Modafinil.

Medwatch alert: Omalizumab.


15-10-2014: AHFS Drug Information October 2014 update

This update contains 1 new monograph and 38 revised monographs.

New monographs: Obinutuzumab.

Revised monographs: Formoterol, Imatinib, Darbepoetin Alfa, Anakinra, Gefitinib, Bevacizumab, Erlotinib, Sorafenib, Sunitinib, Dasatinib, Panitumumab, Lapatinib, Arformoterol, Nilotinib, Romiplostim, Eltrombopag, Prasugrel, Pazopanib, Vandetanib, Ipilimumab, Vemurafenib, Rivaroxaban, Indacaterol, Axitinib, Ticagrelor, Ziv-aflibercept, Bosutinib, Regorafenib, Ponatinib, Acetaminophen, Hydrocodone, Dapsone, Ibuprofen, Aspirin, Epoetin Alfa, Atovaquone, Salmeterol, Trastuzumab.


10-9-2014: AHFS Drug Information September 2014 update

This update contains 5 new monographs and 12 revised monographs.

New monographs: Levomilnacipran, Macitentan, Riociguat, Simeprevir, Sofosbuvir.

Revised monographs: Ambrisentan, Boceprevir, Bosentan, Clobazam, Epoprostenol, Iloprost, Quinidine, Romidepsin, Telaprevir, Tigecycline, Treprostinil, Trimethoprim.


13-8-2014: AHFS Drug Information August 2014 update

This update contains 1 new monographs and 32 revised monographs, including MedWatch alerts for 3 monographs.

New monographs: Afatinib.

Revised monographs: Adalimumab, Anticonvulsants General Statement, Antivenin (Micrurus fulvius) (Equine), C1-Esterase Inhibitor (Human), Certolizumab, Clobazam, Colchicine, Crofelemer, Darunavir, Denosumab, Dexmedetomidine, Dexmethylphenidate, Dimethyl Fumarate, Docetaxel, Eculizumab, Etomidate, Exemestane, Fingolimod, Haemophilus b Vaccine, Hydromorphone, Immunization Schedules, Immunobiologic Agents Available from the CDC, Ingenol Mebutate, Leflunomide, Methylphenidate, Ofatumumab, Olmesartan, Propofol, Raltegravir, Rituximab, Salicylic Acid, Teriflunomide.

Medwatch alerts: Docetaxel, Salicylic Acid, Olmesartan.


9-7-2014: AHFS Drug Information July 2014 update

This update contains 2 new monographs and 18 revised monographs, including MedWatch alerts for 2 monographs.

New monographs: Ospemifene, Linaclotide.

Revised monographs: Eszopiclone, Dabigatran, Ustekinumab, Dimethyl Fumarate, Acetaminophen, Potassium Iodide, Papaverine, Antimuscarinics/Antispasmodics General Statement, Hyoscyamine, Glycopyrrolate, Scopolamine, Atropine, Atracurium, Vecuronium, Antivenin (Micrurus fulvius) (Equine), Esmolol, Anastrozole, Letrozole.

Medwatch alerts: Dabigatran, Eszopiclone.


14-5-2014: AHFS Drug Information May 2014 update

This update contains 3 new monographs and 17 revised monographs, including a MedWatch alert for 1 monograph.

New monographs: Dextromethorphan and Quinidine, Hydroxyethyl Starch 130/0.4, Rotigotine.

Revised monographs: Moxifloxacin, Gemifloxacin, Sorafenib, Doripenem, Brentuximab, Acetaminophen, Codeine (Opiate Agonists), Albuterol/Levalbuterol, Quinidine, Codeine (Antitussives), Dextromethorphan, Guaifenesin, Aspirin, Penicillin G Benzathine, Filgrastim Tbo-filgrastim, Omeprazole, Sildenafil.

Medwatch alert: Sildenafil.


9-4-2014: AHFS Drug Information April 2014 update

This update contains 15 revised monographs.

Revised monographs: Atovaquone and Proguanil, Varenicline, Artemether and Lumefantrine, Boceprevir, Telaprevir, Naphazoline, Chloroquine, Hydroxychloroquine, Primaquine, Pyrimethamine, Quinine Sulfate, Oxymetazoline, Tetrahydrozoline, Ketoconazole, Mefloquine.


12-3-2014: AHFS Drug Information March 2014 update

This update contains 5 new monographs and 6 revised monographs, including MedWatch alerts for 3 monographs and also an annual update completed for Anti-Infectives available from CDC.

New monographs: Dabrafenib, Trametinib Dimethyl Sulfoxide, Apixaban, Lorcaserin, Prothrombin Complex Concentrate.

Revised monographs: Vitamin A, Vitamin D Analogs General Statement, Anti-infectives Available from the CDC.

Medwatch alerts: Acetaminophen, Saline laxatives, Saxagliptin.


11-2-2014: AHFS Drug Information February 2014 update

This update contains 4 new monographs and 12 revised monographs, including MedWatch alerts for 3 monographs, and also an annual update for US immunization schedules and CDC immunobiologics listings.

New monographs: Crofelemer, Dimethyl Fumarate, Ingenol Mebutate, Teriflunomide.

Revised monographs: Antivenin (Micrurus fulvius) (Equine), C1-Esterase Inhibitor (Human), Clobazam, Denosumab, Dexmethylphenidate, Eculizumab, Fingolimod, Haemophilus b Vaccine, Leflunomide, Immunization Schedules, Immunobiologic Agents Available from the CDC, Methylphenidate.

Medwatch alerts: Clobazam, dexmethylphenidate, methylphenidate.


15-1-2014: AHFS Drug Information January 2014 update

This update contains 4 new monographs and 43 revised monographs, including MedWatch alerts for 4 monographs, a REMS added to morphine, and guideline updates for iron sucrose, iron dextran, methimazole, sodium ferric gluconate, and desirudin.

New monographs: Alogliptin, Canagliflozin, Pasireotide, Teduglutide.

Revised monographs: Abciximab, Acetaminophen, Adenosine, Anticonvulsants General Statement, Clozapine, Corticosteroids General Statement, Dalteparin, Desirudin, EENT Preparations, Enoxaparin, Eptifibatide, Exenatide, Factor IX, Factor IX Complex, Flunisolide, Fondaparinux, Gastrointestinal Drugs, Hetastarch, Hormones and Synthetic Substitutes, Iron Dextran, Iron Sucrose, Linagliptin, Liraglutide, Magnesium Sulfate, Methimazole, Miscellaneous Therapeutic Agents, Morphine, Olanzapine, Olmesartan, Phenytoin, Propylthiouracil, Regadenoson, Rosiglitazone, Saxagliptin, Sildenafil, Sitagliptin, Sodium Ferric Gluconate, Sodium Oxybate, Tirofiban, Tolvaptan, Unoprostone, Valproate/Divalproex, Warfarin, Zolpidem.

Medwatch alerts: Adenosine, Dalteparin, Enoxaparin, Regadenoson.


11-12-2013: AHFS Drug Information December 2013 update

This update contains 7 new monographs and 37 revised monographs.

New monographs: Aclidinium, Ado-Trastuzumab Emtansine, Bosutinib, Cabozantinib, Elvitegravir and Cobicistat, Influenza Vaccine Recombinant, Pomalidomide.

Revised monographs: Amphotericin B, Anti-infective Agents, Antineoplastic Agents, Atracurium, Autonomic Drugs, Cefaclor, Cefadroxil, Cefditoren, Cefprozil, Cefpodoxime, Ceftazidime, Cefuroxime, Cephalexin, Cephalosporins General Statement, Ciprofloxacin, Everolimus, Iodine, Influenza Vaccine Live Intranasal, Influenza Virus Vaccine Inactivated, Lenalidomide, Levofloxacin, Pancuronium, Neuromuscular Blocking Agents General Statement, Norfloxacin, Ofloxacin, Penicillin G Benzathine, Penicillin G Potassium, Penicillin G Sodium, Penicillin G Procaine, Ponatinib, Preface to Penicillins, Rocuronium, Serums, Toxoids, and Vaccines, Succinylcholine, Trastuzumab, Thalidomide, Vecuronium, Voriconazole.


14-11-2013: AHFS Drug Information November 2013 update

This update contains 6 new monographs and 14 revised monographs, including MedWatch alerts for 3 monographs.

New monographs: Bedaquiline, Carfilzomib, Enzalutamide, Omacetaxine, Mirabegron, Ziv-aflibercept.

Revised monographs: Cefazolin, Cefdinir, Cefixime, Cefotaxime, Ceftibuten, Ceftriaxone, Fingolimod, Ofatumumab, Rituximab, Rivaroxaban, Vecuronium, Verapamil, Vincristine, Zidovudine.

Medwatch alerts: Fingolimod, Ofatumumab, Rituximab.


9-10-2013: AHFS Drug Information October 2013 update

This update contains 18 revised monographs and 2 new monographs

This update contains 18 revised monographs and 2 new monographs, including MedWatch alerts for 10 monographs.

For a list of the monographs in this update, click here (PDF).


10-9-2013: AHFS Drug Information September 2013 update

This update contains 16 revised monographs and 2 new monographs

This update contains 16 revised monographs and 2 new monograph, including MedWatch alerts for 3 monographs.

For a list of the monographs in this update, click here (PDF).


14-8-2013: AHFS Drug Information August 2013 update

This update contains 8 revised monographs and 1 new monograph

This update contains 8 revised monographs and 1 new monograph, including MedWatch alerts for 4 monographs.

For a list of the monographs in this update, click here (PDF).


9-7-2013: AHFS Drug Information July 2013 update

This update contains 19 revised monographs and 3 new monographs

This update contains 19 revised monographs and 3 new monographs.

For a list of the monographs in this update, click here (PDF).


11-6-2013: AHFS Drug Information June 2013 update

This update contains 9 revised monographs and 3 new monographs

This update contains 9 revised monographs and 3 new monographs.

For a list of the monographs in this update, click here (PDF).


15-5-2013: AHFS Drug Information May 2013 update

This update contains 17 revised monographs

This update contains 17 revised monographs, including MedWatch alerts from March.

For a list of the monographs in this update, click here (PDF).


10-4-2013: AHFS Drug Information annual update 2013

This update contains 34 revised monographs and 4 new monographs

This update contains 34 revised monographs and 4 new monographs, including MedWatch alerts for 8 monographs.

For a list of the monographs in this update, click here (PDF).


18-1-2013: AHFS Drug Information January 2013 update

This update contains ~100 revised and 13 new monographs

This update contains 13 new monographs, and nearly 100 revised monographs including MedWatch alerts from December.

For a list of the monographs in this update, click here (PDF).


13-11-2012: AHFS Drug Information November 2012 update

This update contains 32 revised monographs

This update contains 32 revised monographs, including MedWatch alerts from September and October.

For a list of the monographs in this update, click here (PDF).


11-9-2012: AHFS Drug Information September 2012 update

This update contains 3 new and 11 revised monographs

This update contains 3 new and 11 revised monographs, including MedWatch alerts from August.

For a list of the monographs in this update, click here (PDF).


14-8-2012: AHFS Drug Information August 2012 update

This update contains 13 revised monographs

This update contains 13 revised monographs, including MedWatch alerts from July.

For a list of the monographs in this update, click here (PDF).


12-7-2012: AHFS Drug Information July 2012 update

This update contains 13 revised monographs.

This update contains 13 revised monographs, including MedWatch alerts from May and June.

Medwatch notice for azithromycin, cefepime and ondansetron. Removed Medwatch notices for amlodipine, hydrochlorothiazide. Updated labeling for rituximab, ibritumomab, pamidronate and crotalidae immune fab. Updated REMS information for alosetron, ecallantide and buprenorphine.

For a list of the monographs in this update, click here (PDF).


15-5-2012: AHFS Drug Information May 2012 update

This update contains 43 revised monographs and 1 new monograph

This update contains 43 revised monographs and 1 new monograph, including MedWatch alerts from March and April.

For a list of the monographs in this update, click here (PDF).


13-3-2012: AHFS Drug Information annual update 2012

This update contains 46 revised monographs and 2 new monographs

This update contains 46 revised monographs and 2 new monographs.

For a list of the monographs in this update, click here (PDF).


10-1-2012: AHFS Drug Information January 2012 update

This update contains 73 revised monographs and 9 new monographs

This update contains 73 revised monographs and 9 new monographs.

For a list of the monographs in this update, click here (PDF).


14-12-2011: AHFS Drug Information December 2011 update

This update contains 54 revised and 7 new monographs

This update contains 7 new monographs and 54 revised monographs, including MedWatch alerts from November.

For a list of the monographs in this update, click here (PDF).


16-11-2011: AHFS Drug Information November 2011 update

This update contains 1 new monograph and 21 revised monographs

This update contains 1 new monograph and 21 revised monographs, and many with added REMS statements.

For a list of the monographs in this update, click here (PDF).


11-10-2011: AHFS Drug Information October 2011 update

This update contains 16 revised monographs and 2 new monographs

This update contains 16 revised and 2 new monographs, including MedWatch alerts from September.

For a list of the monographs in this update, click here (PDF).


13-9-2011: AHFS Drug Information September 2011 update

AHFS Drug Information updated with 22 revised and 7 new monographs

This update contains 22 revised and 7 new monographs, including MedWatch alerts from July and August.

For a list of the monographs in this update, click here (PDF).


14-7-2011: AHFS Drug Information July 2011 update

AHFS Drug Information updated with 25 revised monographs

This update contains 15 revised monographs, including MedWatch alerts from May.

For a list of the monographs in this update, click here (PDF).


13-6-2011: AHFS Drug Information June 2011 update

AHFS Drug Information updated with 9 revised and 1 new monograph

This update contains 9 revised and 1 new monograph.

For a list of the monographs in this update, click here (PDF).


6-5-2011: AHFS Drug Information May 2011 update

AHFS Drug Information updated with 17 revised and 2 new monographs

This update contains 15 revised monographs, including MedWatch alerts from April.

For a list of the monographs in this update, click here (PDF).


15-4-2011: AHFS Drug Information April 2011 update

AHFS Drug Information updated with 39 revised monographs

This update contains 39 revised monographs, including MedWatch alerts from March.

For a list of the monographs in this update, click here (PDF).


21-3-2011: AHFS Drug Information Annual update 2011

AHFS Drug Information updated with 35 revised and 6 new monographs

This update contains 35 revised and 6 new monographs, including MedWatch alerts from February. Two monographs have been deleted.

For a list of the monographs in this update, click here (PDF).


13-1-2011: AHFS Drug Information January 2011 update

AHFS Drug Information updated with 64 revised and 3 new monographs

This update contains 3 new and 64 revised monographs, including MedWatch alerts from December.

For a list of the monographs in this update, click here (PDF).


13-12-2010: AHFS Drug Information December 2010 update

AHFS Drug Information updated with 36 revised and 3 new monographs

This update contains 36 revised monographs and 3 new monographs, including MedWatch alerts from November.

For a list of the monographs in this update, click here (PDF).

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11-11-2010: AHFS Drug Information November 2010 update

AHFS Drug Information updated with 16 revised and 1 new monograph

This update contains 16 revised and 1 new monograph, including MedWatch alerts from October.

For a list of the monographs in this update, click here (PDF).


12-10-2010: AHFS Drug Information October 2010 update

AHFS Drug Information updated with 10 revised and 2 new monographs

This update contains 10 revised and 2 new monographs.

For a list of the monographs in this update, click here (PDF).


6-9-2010: AHFS Drug Information September 2010 update

AHFS Drug Information updated with 15 revised and 6 new monographs

This update contains 15 revised and 6 new monographs, including MedWatch alerts from August.

For a list of the monographs in this update, click here (PDF).


10-8-2010: AHFS Drug Information August 2010 update

AHFS Drug Information updated with 1 new and 17 revised monographs

This update contains 1 new and 17 revised monographs, including MedWatch alerts from July.

For a list of the monographs in this update, click here (PDF).


13-7-2010: AHFS Drug Information July 2010 update

AHFS Drug Information updated with 9 revised and 4 new monographs

This update contains 9 revised monographs and 4 new monographs, including MedWatch alerts from June.

For a list of the monographs in this update, click here (PDF).


15-6-2010: AHFS Drug Information June 2010 update

AHFS Drug Information updated with 17 revised monographs

This update contains 17 revised monographs, including MedWatch alerts from May.

For a list of the monographs in this update, click here (PDF).


7-5-2010: AHFS Drug Information May 2010 update

AHFS Drug Information updated with 6 revised and 1 new monograph

This update contains 6 revised and 1 new monograph, including MedWatch alerts from April.

For a list of the monographs in this update, click here (PDF).


13-4-2010: AHFS Drug Information April 2010 update

AHFS Drug Information updated with 14 revised monographs

This update contains 14 revised monographs, including MedWatch alerts from March.

For a list of the monographs in this update, click here (PDF).


6-4-2010: AHFS Drug Information Annual update 2010

AHFS Drug Information updated with MedWatch alerts and 3 new monographs

This update contains 3 new monographs, and MedWatch alerts for over 30 drugs.

For further details, click here (PDF).


7-1-2010: AHFS Drug Information January 2010 update

AHFS Drug Information updated with 20 revised monographs

This update contains 20 revised monographs.

For a list of the monographs in this update, click here (PDF).


8-12-2009: AHFS Drug Information December 2009 update

AHFS Drug Information updated with 4 new and 40 revised monographs

This update contains 4 new and 40 revised monographs, including MedWatch alerts from November.

For a list of the monographs in this update, click here (PDF).


13-11-2009: AHFS Drug Information November 2009 update

AHFS Drug Information updated with 23 revised monographs

This update contains 23 revised monographs, including MedWatch alerts from October.

For a list of the monographs in this update, click here (PDF).


19-10-2009: AHFS Drug Information October 2009 update

AHFS Drug Information updated with 4 new and 30 revised monographs

This update contains 4 new and 30 revised monographs.

For further details and a list of the monographs in this update, click here (PDF).


7-9-2009: AHFS Drug Information September 2009 update

AHFS Drug Information updated with 1 new monograph and 22 revised monographs

This update contains 1 new and 22 revised monographs, including MedWatch alerts from August.

For a list of the monographs in this update, click here (PDF).


7-8-2009: AHFS Drug Information August 2009 update

AHFS Drug Information updated with 5 new monographs and 36 revised monographs

This update contains 36 revised and 5 new monographs, including MedWatch alerts from July.

For a list of the monographs in this update, click here (PDF).


13-7-2009: AHFS Drug Information July 2009 update

AHFS Drug Information updated with 4 new monographs and 20 revised monographs

This update contains 4 new and 20 revised monographs, including MedWatch alerts from June.

For a list of the monographs in this update, click here (PDF).


18-6-2009: AHFS Drug Information June 2009 update

AHFS Drug Information updated with 15 revised monographs

This update contains 15 revised monographs, including MedWatch alerts from May.

For a list of the monographs in this update, click here (PDF).


4-6-2009: AHFS Drug Information May 2009 update

AHFS Drug Information updated with 2 new monographs and 9 revised monographs

This update contains 2 new and 9 revised monographs, including MedWatch alerts from April and updated H1N1 virus treatment recommendations.

For a list of the monographs in this update, click here (PDF).


8-4-2009: AHFS Drug Information April 2009 update

AHFS Drug Information updated with 19 revised monographs

This update contains 19 revised monographs, including MedWatch alerts from March.

For a list of the monographs in this update, click here (PDF).


5-3-2009: AHFS Drug Information March 2009 update

AHFS Drug Information updated with 9 revised monographs

This update contains 9 revised monographs, with MedWatch alerts from February.

For a list of the monographs in this update, click here (PDF).


27-2-2009: First 2009 update of AHFS Drug Information

AHFS Drug Information update corresponds to the 2009 print edition

Over 700 monographs were revised for inclusion in the 2009 print edition of AHFS Drug Information. These revisions incorporate new or updated therapeutic guidelines from:

  • the American College of Chest Physicians (ACCP) Evidence-Based Clinical Practice Guidelines on Antithrombotic and Thrombolytic Therapy
  • US Department of Health and Human Services (HHS) guidelines for the management of HIV infection in adults and children and guidelines for use of antiretroviral drugs in pregnant HIV-1-infected women for maternal health and interventions to reduce perinatal HIV-1 transmission
  • multiple guidelines regarding screening and treating pediatric patients for lipid disorders from the National Cholesterol Education Program (NCEP), the American Academy of Pediatrics (AAP), and the American Heart Association (AHA) among others
  • recommendations for prevention and treatment of opportunistic infections in HIV-infected individuals approved by Centers for Disease Control and Prevention (CDC), National Institutes of Health (NIH), and the HIV Medicine Association of the Infectious Diseases Society of America (IDSA)
  • Centers for Disease Control and Prevention (CDC) for influenza vaccination and management
  • the latest (January 2009) US Recommended Immunization Schedules for Children and Adolescents, which was issued by the CDC, AAP, and American Academy of Family Physicians (AAFP), as well as the revised (January 2009) US Recommended Immunization Schedules for Adults that incorporates the recommendations of CDC, AAFP, American College of Physicians (ACP), and ACOG
  • US Centers for Disease Control and Prevention (CDC) health information for international travel
  • AHA and AAP regarding the need for routine ECG screening in all pediatric patients being considered for or currently receiving stimulant therapy.

Dozens of other monographs were revised based on FDA MedWatch notices.

For a full list of new and revised monographs in this online update, click here (PDF).


9-12-2008: AHFS Drug Information December 2008 update

AHFS Drug Information updated with 4 new and 47 revised monographs

Highlights of this update include:

  • Nebivolol and Nilotinib were expanded from FirstReleases to Overviews.
  • Altretamine and Pegaspargase were expanded from Overviews to a full-length monographs.
  • Adefovir was revised based on updated treatment guidelines and labeling.
  • The other monographs were revised based on labeling changes and recent MedWatch alerts.

For a full list of new and revised monographs in this update, click here (PDF).


14-11-2008: AHFS Drug Information November 2008 update

AHFS Drug Information updated with 83 revised monographs

Doripenem and Mometasone were expanded from FirstReleases to Overview monographs. MedWatch alerts were added to 9 monographs (Efalizumab, Epoetin alfa, Atorvastatin, HMG-CoA Reductase Inhibitors GS, Rosuvastatin, Lovastatin, Pravastatin, Simvastatin, and Fluvastatin). 6 monographs were updated to include the 2008-2009 influenza season guidelines (Amantadine, Rimantadine, Zanamivir, Oseltamivir, and Influenza Virus Vaccines [Live and Inactivated]).

For a full list of these monographs, click here (PDF).


3-10-2008: AHFS Drug Information October 2008 update

AHFS Drug Information updated with 13 revised and 2 new monographs

This update contains 13 revised and 2 new monographs. For full details, click here (PDF).


8-9-2008: AHFS Drug Information September 2008 update

AHFS Drug Information updated with 11 revised and 1 new monograph

This update contains 11 revised and 1 new monograph. For full details, click here (PDF).


18-8-2008: AHFS Drug Information August 2008 update

AHFS Drug Information updated with 19 revised and 2 new monographs

This update contains 19 revised and 2 new monographs. For full details, click here (PDF).

8-7-2008: AHFS Drug Information July 2008 update

AHFS Drug Information updated with 17 revised monographs

This update contains 17 revised monographs. For full details, click here (PDF).


18-6-2008: AHFS Drug Information June 2008 update

AHFS Drug Information updated with 7 revised monographs and 1 new monograph

This update contains 7 revised monographs and 1 new monograph. A MedWatch notice was added to varenicline, aprotinin, and mycophenolate.

Full details (PDF).


8-5-2008: AHFS Drug Information May 2008 update

AHFS Drug Information updated with 10 revised monographs

This update contains 10 revised monographs. The monographs for maraviroc and etravirine were expanded from firstReleases to an Overviews and a MedWatch notice was added to etanercept.

Full details (PDF).


22-4-2008: AHFS Drug Information April 2008 update

AHFS Drug Information updated with 15 revised monographs and 1 new monograph

This update contains 15 revised monographs and one new monograph. Two monographs were revised due to FDA MedWatch notices. The monograph for raltegravir was expanded from a firstRelease to an Overview.

Full details (PDF).


20-3-2008: First 2008 update

AHFS Drug Information update corresponds to the 2008 print edition

This update, corresponding to the 2008 print edition, has been updated extensively, and includes MedWatch notices that were issued in January/February 2008.

Full details (PDF).


19-12-2007: AHFS Drug Information December 2007 update

AHFS Drug Information updated with 61 revised monographs

This update contains 61 revised monographs. The monographs for telbivudine, lapatinib, and paliperidone were expanded from firstReleases to Overviews.

Full details (PDF).


6-11-2007: AHFS Drug Information November 2007 update

AHFS Drug Information updated with 64 revised and 2 new monographs

This update contains 64 revised monographs. It also contains 2 new monographs: maraviroc and raltegravir.

Full details (PDF).


17-10-2007: AHFS Drug Information October 2007 update

AHFS Drug Information updated with 21 revised and 3 new monographs

This update contains 3 new monographs and 21 revisions. Posaconazole was upgraded from a FirstRelease monograph to an Overview monograph. The new monographs are:
  • Temsirolimus
  • Levocetirizine
  • Eculizumab
The revised monographs are:
  • Risedronate
  • Zoledronic Acid
  • Clopidogrel
  • Pergolide
  • Ibritumomab
  • Budesonide
  • Ibandronate
  • Posaconazole
  • Azathioprine
  • Haloperidol
  • Trimipramine
  • Desipramine
  • Imipramine
  • Fentanyl
  • Pyrethrins with Piperonyl Butoxide (Topical)
  • Etidronate
  • Ceftriaxone
  • Terconazole (Topical)
  • Pamidronate
  • Valacyclovir
  • Alendronate

13-9-2007: AHFS Drug Information September 2007 update

AHFS Drug Information updated with 19 revised and 5 new monographs

This update contains 5 new monographs and 19 revisions. Anidulafungin was upgraded from a FirstRelease monograph to an Overview monograph.


9-8-2007: AHFS Drug Information August 2007 update

AHFS Drug Information updated with 8 revised and 2 new monographs

This update contains 8 revised monographs. It also contains 2 new monographs: aliskirin hemifumarate and lisdexamfetamine dimesylate. Aliskirin has been preliminarily assigned to class 24:32. However, a new sub-classification 24:32.40 - "Renin Inhibitors" - will be created, and this drug will be moved to the new class in due course.


19-7-2007: AHFS Drug Information July 2007 update

AHFS Drug Information updated with 17 revised and 1 upgraded monograph

This update contains 17 revised monographs. It also includes 1 monograph (sorafenib) that was upgraded from a firstRelease to an Overview.


6-6-2007: AHFS Drug Information June 2007 update

AHFS Drug Information updated with 6 revised and 1 upgraded monograph

This update contains 6 revised monographs (pegaptanib (EENT), metronidazole, minoxidil, rimantadine, zanamivir, oseltamivir) and 1 monograph (ranolazine) that was upgraded from a firstRelease to an Overview.

14-5-2007: AHFS Drug Information May 2007 update

AHFS Drug Information updated with 9 revised monographs

This update contains 9 revised monographs: docosanol (topical), tizanidine, telithromycin, rotavirus vaccine live oral, acetaminophen, estrogen-progestin combinations, trimethobenzamide, norfloxacin, ofloxacin.

Of these, 3 monographs were revised due to Medwatch notices from the FDA (telithromycin, tizanidine, trimethobenzamide, and rotavirus vaccine).


19-4-2007: AHFS Drug Information April 2007 update

AHFS Drug Information updated with 2 new monographs and 39 revised monographs

This update contains 2 new monographs and 39 revised monographs. A total of 21 monographs were revised due to Medwatch notices from the FDA (atomoxetine, cyclosporine, darbepoetin, dexmethylphenidate, dextroamphetamine, entecavir, epoetin alfa, eszopiclone, interferon gamma, linezolid, methylphenidate, mycophenolate, omalizumab, pioglitazone, ramelteon, rosiglitazone, tacrolimus, temazepam, triazolam, zaleplon, zolpidem). In addition, the new monograph, Sitagliptin, has been added to a new therapeutic class: "68:20.05 - Dipeptidyl Peptidase-4 (DPP-4) Inhibitors".


9-3-2007: First 2007 update

AHFS Drug Information updated with 28 new monographs

This update, corresponding to the 2007 print edition, has been updated extensively, incorporating revised information on uses, therapeutic perspectives, cautions, drug interactions, new products, and other new developments. Each year more than 60% of the monographs are revised. The coverage in the 2007 edition has been expanded by 28 new drug monographs.

18-12-2006: AHFS Drug Information December 2006 update

AHFS Drug Information updated with 71 revised and 4 new monographs

This update contains 71 revised monographs and 4 new monographs (posaconazole, dasatinib, rasagiline, ranibizumab). Oseltamivir was revised due to an FDA MedWatch notice. Other revisions of note were made due to updated guidelines and treatment recommendations from the National Lipid Association (HMG CoA Redutase Inhibitors) and the American Heart Association CPR guidelines (mexiletine, flecainide, ibutilide, and propafenone).

28-11-2006: AHFS Drug Information November 2006 update

AHFS Drug Information updated with 40 revised monographs

This update contains 40 revised monographs. Two monographs (decitabine and varenicline) were enhanced from a firstRelease to an overview format (additional precautionary information and drug interactions). Five monographs were revised due to FDA MedWatch notices (imatinib, lamotrigine, meningococcal vaccine, warfarin, and venlafaxine).

18-10-2006: AHFS Drug Information October 2006 update

AHFS Drug Information updated with 19 monographs

This update contains 19 monographs, consisting of 1 new monograph, and 18 revised monographs. Of these, 5 monographs were revised due to MedWatch notices (aspirin, bevacizumab, estrogens, ibuprofen, and salicylates general statement).

26-9-2006: AHFS Drug Information September 2006 update

AHFS Drug Information updated with 4 new and 34 revised monographs

This update contains 38 monographs, consisting of 4 new monographs (insulin detemir, anidulafungin, decitabine, varenicline), and 34 revised monographs. Three monographs were expanded from AHFS firstReleases to AHFS Overviews (nelarabine, pramlintide, nepafenac). Three monographs were revised due to a MedWatch notice from the FDA regarding amphetamine use and sudden death in association with CNS stimulant treatment at usual doses in children and adolescents with structural cardiac abnormalities or other serious heart problems. 12 monographs were revised with new product listings, and the Estrogen-Progestin Combination monograph was revised to include information on the recently approved "Plan B" for postcoital contraception.

11-9-2006: AHFS Drug Information August 2006 update

AHFS Drug Information updated with 31 revised monographs

This update contains 3 new monographs and 31 revised monographs. Of these, 16 monographs were revised due to MedWatch alerts. Most of these alerts related to a new warning from the FDA regarding the occurrence of serotonin syndrome in individuals taking medications commonly used to treat migraine headaches with certain types of antidepressants and mood disorder medications.

18-7-2006: AHFS Drug Information July 2006 update

AHFS Drug Information updated with 10 revised monographs

The New England Journal of Medicine recently published an article reporting that infants whose mothers had taken an angiotensin-converting enzyme inhibitor (ACE inhibitors) drug during the first trimester of pregnancy had an increased risk of major congenital malformations, compared with infants who had not undergone first trimester exposure to ACE inhibitor drugs. The FDA-approved labels recommends discontinuing the ACEI as soon as possible if a patient becomes pregnant. ACE inhibitor drugs are labeled pregnancy category C for the first trimester of pregnancy, and are labeled pregnancy category D during the second and third trimesters. Healthcare professionals should take these findings into consideration with other information about a patient's medical situation when prescribing ACE inhibitors. At this time, based on this one observational study, the FDA does not plan to change the pregnancy categories for ACE inhibitors. FDA will work with the Agency for Healthcare Quality and Research to identify other potential sources of data that will help determine the degree of risk associated with first trimester exposures to these drugs. This prompted revisions to the 10 ACEI monographs in AHFS Drug Information.

12-6-2006: AHFS Drug Information June 2006 update

AHFS Drug Information updated with new and revised monographs and new precautionary information

Seven new monographs have been added to the database, reflecting recent new drug approvals by the FDA:

  • Omega-3-acid Ethyl Esters, approved as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with TG levels >/= 500 mg/dL
  • Abatacept, approved for reducing the signs and symptoms of rheumatoid arthritis (RA), inducing major clinical response, slowing the progression of structural damage, and improving physical function in adult patients with moderately to severely active RA who have had an inadequate response to one or more disease-modifying anti-rheumatic drugs (DMARDs), such as methotrexate (MTX) or tumor necrosis factor (TNF) antagonists
  • Mecasermin, approved for long-term treatment of a rare type of hormone deficiency that causes children to be much shorter than their peers and to grow at a much slower rate; a human insulin-like growth factor-1 (IGF-1) produced by recombinant DNA technology
  • Lenalidomide, approved for myelodysplastic syndrome (but a supplemental new drug application (sNDA) has already been filed for relapsed or refractory multiple myeloma)
  • Sorafenib, approved for advanced renal cell carcinoma (RCC)
  • Lubiprostone, approved for chronic idiopathic constipation
  • Insulin Glulisine, a human insulin analog that is a rapid-acting, parenteral blood glucose lowering agent

The following monographs have been updated to include new precautionary information issued by the FDA (MedWatch Notices): Gatifloxacin, Telithromycin, Aprotinin, Nimodipine, Clozapine, Benzocaine, Pimecrolimus, Denileukin, Bosentan, Mifepristone, Paroxetine, Rosiglitazone, and Immune Globulin.

In addition, 156 other monographs have been revised, including updated product listings.


8-5-2006: First release on MedicinesComplete

AHFS Drug Information provides up-to-date information on tens of thousands of drug products

The coverage of the 2006 edition has been expanded to include 31 new drug monographs:

  • Increased granularity of the AHFS Classification and CMS Medicare Part D recognition
  • Extensively revised product listings
  • Current authoritative therapeutic guidelines updated
  • Major cautionary information revised

8-5-2006: Now Available - AHFS

American Hospital Formulary Service Now Available

The American Hospital Formulary Service (AHFS)is now available on MedicinesComplete.

For further information, please see (PDF).

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